The Journal of Clinical Investigation is a premier venue for discoveries in basic and clinical biomedical science that will advance the practice of medicine.

The JCI was founded in 1924 and is published by the ASCI, a nonprofit honor organization of physician-scientists incorporated in 1908. See the JCI's Wikipedia entry for detailed information.

• Impact Factor: 12.282 (2018). The JCI is one of the top journals in the “Medicine, Research & Experimental” category.
• Broad readership and scope. The JCI reaches readers across a wide range of medical disciplines and sectors. The journal publishes basic and phase I/II clinical research submissions in all biomedical specialties, including Autoimmunity, Gastroenterology, Immunology, Metabolism, Nephrology, Neuroscience, Oncology, Pulmonology, Vascular Biology, and many others.
• Open access. All research is available to the public for free. The JCI deposits published research articles in PubMed Central, which satisfies the NIH Public Access Policy and other similar funding agency requirements.

Submit your work

• The journal considers research submissions in several categories.
• Start your submission by accessing your JCI author account. If you don’t have an account yet, sign up here.
• Click here for information on submission, manuscript and figure preparation, and editorial policies.
• For any communication with us, reference the tracking number assigned by the journal noted in the acknowledgment of your submission. If you do not have this information, reference the manuscript title and corresponding author’s name. Send email to staff@the-jci.org or call 734-222-6050.
• To avoid confusion regarding correspondence, inquiries, and decisions, the JCI will typically communicate only with corresponding authors of submissions.