[HTML][HTML] The interferon-induced transmembrane proteins, IFITM1, IFITM2, and IFITM3 inhibit hepatitis C virus entry
SK Narayana, KJ Helbig, EM McCartney… - Journal of Biological …, 2015 - ASBMB
The interferon-induced transmembrane (IFITM) family of proteins have recently been
identified as important host effector molecules of the type I interferon response against
viruses. IFITM1 has been identified as a potent antiviral effector against hepatitis C virus
(HCV), whereas the related family members IFITM2 and IFITM3 have been described to
have antiviral effects against a broad range of RNA viruses. Here, we demonstrate that
IFITM2 and IFITM3 play an integral role in the interferon response against HCV and act at …
identified as important host effector molecules of the type I interferon response against
viruses. IFITM1 has been identified as a potent antiviral effector against hepatitis C virus
(HCV), whereas the related family members IFITM2 and IFITM3 have been described to
have antiviral effects against a broad range of RNA viruses. Here, we demonstrate that
IFITM2 and IFITM3 play an integral role in the interferon response against HCV and act at …