[PDF][PDF] Dendritic spine geometry: functional implication and regulation
Y Hayashi, AK Majewska - Neuron, 2005 - cell.com
Neuron, 2005•cell.com
Dendritic spines are tiny protrusions on dendritic shafts where most excitatory synapses are
located. Recent advances in imaging technologies have given us great insight into the
function of spines as biochemical compartments. Here we review recent evidence
suggesting that the geometry of dendritic spines controls postsynaptic calcium signaling and
is bidirectionally regulated during synaptic plasticity.
located. Recent advances in imaging technologies have given us great insight into the
function of spines as biochemical compartments. Here we review recent evidence
suggesting that the geometry of dendritic spines controls postsynaptic calcium signaling and
is bidirectionally regulated during synaptic plasticity.
Dendritic spines are tiny protrusions on dendritic shafts where most excitatory synapses are located. Recent advances in imaging technologies have given us great insight into the function of spines as biochemical compartments. Here we review recent evidence suggesting that the geometry of dendritic spines controls postsynaptic calcium signaling and is bidirectionally regulated during synaptic plasticity.
cell.com