A common core microbiota between obese individuals and their lean relatives? Evaluation of the predisposition to obesity on the basis of the fecal microflora profile

M Elli, O Colombo, A Tagliabue - Medical hypotheses, 2010 - Elsevier
Obesity represents a crucial social problem in developed countries as a cause of multiple
metabolic abnormalities. The exact etiology of this multifactorial disease is still unknown.
The impact of dietary habits and lifestyle is currently under investigation but the role of other
predisposing factors, such as genetic determinants and familial history, needs still to be
elucidated. Significant alterations in the composition of the intestinal microbiota have been
recently identified in obese mice, suggesting an involvement of gut microbes in obesity. In …