Neutrophil recruitment mediated by sphingosine 1-phosphate (S1P)/S1P receptors during chronic liver injury
X Zhao, L Yang, N Chang, L Hou, X Zhou, C Dong… - Cellular …, 2021 - Elsevier
Excessive neutrophils are recruited to damaged tissue and cause collateral injury under
chronic inflammatory conditions. Sphingosine 1-phosphate (S1P) modulates kinds of
physiological and pathological actions by inducing recruitment of various cell types through
S1P receptors (S1PRs). This study aimed to detect the S1P/S1PRs-mediated effects on
neutrophil recruitment during chronic liver inflammation. In present study, increased
neutrophils originated from bone marrow (BM) were detected in liver tissue of BDL-treated …
chronic inflammatory conditions. Sphingosine 1-phosphate (S1P) modulates kinds of
physiological and pathological actions by inducing recruitment of various cell types through
S1P receptors (S1PRs). This study aimed to detect the S1P/S1PRs-mediated effects on
neutrophil recruitment during chronic liver inflammation. In present study, increased
neutrophils originated from bone marrow (BM) were detected in liver tissue of BDL-treated …
