[HTML][HTML] Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review
C Neunert, N Noroozi, G Norman, GR Buchanan… - Journal of Thrombosis …, 2015 - Elsevier
Background The burden of severe bleeding in adults and children with immune
thrombocytopenia (ITP) has not been established. Objectives To describe the frequency and
severity of bleeding events in patients with ITP, and the methods used to measure bleeding
in ITP studies. Patients/Methods We performed a systematic review of all prospective ITP
studies that enrolled 20 or more patients. Two reviewers searched Medline, Embase,
CINAHL and the Cochrane registry up to May 2014. Overall weighted proportions were …
thrombocytopenia (ITP) has not been established. Objectives To describe the frequency and
severity of bleeding events in patients with ITP, and the methods used to measure bleeding
in ITP studies. Patients/Methods We performed a systematic review of all prospective ITP
studies that enrolled 20 or more patients. Two reviewers searched Medline, Embase,
CINAHL and the Cochrane registry up to May 2014. Overall weighted proportions were …